Publications

2018

Reply to 'Bromocriptine for the treatment of peripartum cardiomyopathy: comparison of outcome with a nationwide Danish cohort'.

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Hilfiker-Kleiner D, Sliwa K, Bauersachs J.  Reply to 'Bromocriptine for the treatment of peripartum cardiomyopathy: comparison of outcome with a nationwide Danish cohort'.  Eur Heart J. 2018 Oct 1;39(37):3478.

2018, Peer Reviewed articles

Peripartum Cardiomyopathy: an Update.

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Azibani F, Sliwa K.  Peripartum Cardiomyopathy: an Update.  Curr Heart Fail Rep. 2018 Oct;15(5):297-306.

2018, Peer Reviewed articles

Pulmonary hypertension as seen in a rural area in sub-Saharan Africa: high prevalence, late clinical presentation and a high short-term mortality rate during follow up.

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Dzudie A, Dzekem BS, Tchoumi CT, Aminde LN, Mocumbi AO, Abanda M, Thienemann F, Kengne AP, Sliwa K.  Pulmonary hypertension as seen in a rural area in sub-Saharan Africa: high prevalence, late clinical presentation and a high short-term mortality rate during follow up.  Cardiovasc J Afr. 2018 Jul/Aug 23;29(4):208-212

2018, Peer Reviewed articles

Prevalence, clinical characteristics and outcomes of valvular atrial fibrillation in a cohort of African patients with acute heart failure: insights from the THESUS-HF registry.

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Sani MU, Davison BA, Cotter G, Mayosi BM, Edwards C, Ogah OS, Damasceno A, Ojji DB, Dzudie A, Mondo C, Kouam CK, Suliman A, Yonga G, Ba SA, Maru F, Alemayehu B, Sliwa K.  Prevalence, clinical characteristics and outcomes of valvular atrial fibrillation in a cohort of African patients with acute heart failure: insights from the THESUS-HF registry.  Cardiovasc J Afr. 2018 May/Jun;29(3):139-145.

2018, Peer Reviewed articles

Reducing late maternal death due to cardiovascular disease - A pragmatic pilot study.

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Sliwa K, Azibani F, Baard J, Osman A, Zühlke L, Lachmann A, Libhaber E, Chin A, Ntsekhe M, Soma-Pillay P, Johnson MR, Roos-Hesselink J, Anthony J.  Reducing late maternal death due to cardiovascular disease - A pragmatic pilot study.  Int J Cardiol. 2018 Dec 1;272:70-76.

2018, Peer Reviewed articles

Bromocriptine treatment in patients with peripartum cardiomyopathy and right ventricular dysfunction.

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Haghikia A, Schwab J, Vogel-Claussen J, Berliner D, Pfeffer T, König T, Zwadlo C, Moulig VA, Franke A, Schwarzkopf M, Ehlermann P, Pfister R, Michels G, Westenfeld R, Stangl V, Kühl U, Podewski E, Kindermann I, Böhm M, Sliwa K, Hilfiker-Kleiner D, Bauersachs J.  Bromocriptine treatment in patients with peripartum cardiomyopathy and right ventricular dysfunction.  Clin Res Cardiol. 2018 Aug 18. doi: 10.1007/s00392-018-1355-7

2018, Peer Reviewed articles

The Cape Town Declaration on Access to Cardiac Surgery in the Developing World.

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Zilla P, Bolman RM, Yacoub MH, Beyersdorf F, Sliwa K, Zühlke L, Higgins RSD, Mayosi B, Carpentier A, Williams D.  The Cape Town Declaration on Access to Cardiac Surgery in the Developing World.  S Afr Med J. 2018 Aug 28;108(9):702-704

2018, Peer Reviewed articles

Time to tackle rheumatic heart disease: Data needed to drive global policy dialogues.

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Abouzeid M, Wyber R, La Vincente S, Sliwa K, Zühlke L, Mayosi B, Carapetis J.  Time to tackle rheumatic heart disease: Data needed to drive global policy dialogues.  Glob Public Health. 2018 Sep 7:1-13

2018, Peer Reviewed articles

The Pan-African Society of Cardiology position paper on reproductive healthcare for women with rheumatic heart disease.

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Mocumbi AO, Jamal KK, Mbakwem A, Shung-King M, Sliwa K.  The Pan-African Society of Cardiology position paper on reproductive healthcare for women with rheumatic heart disease.  Cardiovasc J Afr. 2018 Sep 18;29:1-10

2018, Peer Reviwed articles

Global, regional, and national disability-adjusted life-years (DALYs) for 359 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017.

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GBD 2017 DALYs and HALE Collaborators.  Global, regional, and national disability-adjusted life-years (DALYs) for 359 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017.  Lancet. 2018 Nov 10;392(10159):1859-1922.

2018, Peer Reviewed articles

Global, regional, and national age-sex-specific mortality and life expectancy, 1950-2017: a systematic analysis for the Global Burden of Disease Study 2017.

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GBD 2017 Mortality Collaborators.  Global, regional, and national age-sex-specific mortality and life expectancy, 1950-2017: a systematic analysis for the Global Burden of Disease Study 2017.  Lancet. 2018 Nov 10;392(10159):1684-1735.

2018, Peer Reviewed articles

Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980-2017: a systematic analysis for the Global Burden of Disease Study 2017.

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GBD 2017 Causes of Death Collaborators.  Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980-2017: a systematic analysis for the Global Burden of Disease Study 2017.  Lancet. 2018 Nov 10;392(10159):1736-1788

2018, Peer Reviewed articles 

Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017.

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GBD 2017 Disease and Injury Incidence and Prevalence Collaborators.  Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017.  Lancet. 2018 Nov 10;392(10159):1789-1858

2018, Peer Reviewed articles

Population and fertility by age and sex for 195 countries and territories, 1950-2017: a systematic analysis for the Global Burden of Disease Study 2017.

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GBD 2017 Population and Fertility Collaborators.  Population and fertility by age and sex for 195 countries and territories, 1950-2017: a systematic analysis for the Global Burden of Disease Study 2017.  Lancet. 2018 Nov 10;392(10159):1995-2051

2018, Peer Reviewed articles

Measuring progress from 1990 to 2017 and projecting attainment to 2030 of the health-related Sustainable Development Goals for 195 countries and territories: a systematic analysis for the Global Burden of Disease Study 2017.

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GBD 2017 SDG Collaborators.  Measuring progress from 1990 to 2017 and projecting attainment to 2030 of the health-related Sustainable Development Goals for 195 countries and territories: a systematic analysis for the Global Burden of Disease Study 2017.  Lancet. 2018 Nov 10;392(10159):2091-2138.

2018, Peer Reviewed articles

The prognostic significance of the 12-lead ECG in peripartum cardiomyopathy.

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Hoevelmann J, Viljoen CA, Manning K, Baard J, Hahnle L, Ntsekhe M, Bauersachs J, Sliwa K.  The prognostic significance of the 12-lead ECG in peripartum cardiomyopathy.  Int J Cardiol. 2018 Nov 7. pii: S0167-5273(18)33751-3

2018, Peer Reviwed articles

A diagnostic algorithm for pulmonary hypertension due to left heart disease in resource-limited settings: can busy clinicians adopt a simple, practical approach?

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Dzudie A, Kengne AP, Lamont K, Dzekem BS, Aminde LN, Abanda MH, Thienemann F, Sliwa K.  A diagnostic algorithm for pulmonary hypertension due to left heart disease in resource-limited settings: can busy clinicians adopt a simple, practical approach?  Cardiovasc J Afr. 2018 Nov 30;29:1-7.

2018, Peer Reviewed articles

The 10th Biennial Hatter Cardiovascular Institute workshop: cellular protection-evaluating new directions in the setting of myocardial infarction, ischaemic stroke, and cardio-oncology.

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Davidson SM, Arjun S, Basalay MV, Bell RM, Bromage DI, Bøtker HE, Carr RD, Cunningham J, Ghosh AK, Heusch G, Ibanez B, Kleinbongard P, Lecour S, Maddock H, Ovize M, Walker M, Wiart M, Yellon DM.  The 10th Biennial Hatter Cardiovascular Institute workshop: cellular protection-evaluating new directions in the setting of myocardial infarction, ischaemic stroke, and cardio-oncology.  Basic Res Cardiol. 2018 Oct 11;113(6):43

2018, Peer Reviwed articles

Exercise intervention alters HDL subclass distribution and function in obese women.

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Woudberg NJ, Mendham AE, Katz AA, Goedecke JH, Lecour S.  Exercise intervention alters HDL subclass distribution and function in obese women.  Lipids Health Dis. 2018 Oct 10;17(1):232.

2018, Peer Reviewed articles

Melatonin in Heart Failure: A Promising Therapeutic Strategy? 

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Nduhirabandi, F.; Maarman, G.J.  Melatonin in Heart Failure: A Promising Therapeutic Strategy? Molecules 2018, 23(7), 1819

2018, Peer Reviewed articles

An Exercise Intervention to Unravel the Mechanisms Underlying Insulin Resistance in a Cohort of Black South African Women: Protocol for a Randomized Controlled Trial and Baseline Characteristics of Participants. 

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Goedecke JH, Mendham AE, Clamp L, Nono Nankam PA, Fortuin-de Smidt MC, Phiri L, Micklesfield LK, Keswell D, Woudberg NJ, Lecour S, Alhamud A, Kaba M, Lutomia FM, van Jaarsveld PJ, de Villiers A, Kahn SE, Chorell E, Hauksson J, Olsson T. An Exercise Intervention to Unravel the Mechanisms Underlying Insulin Resistance in a Cohort of Black South African Women: Protocol for a Randomized Controlled Trial and Baseline Characteristics of Participants. JMIR Res Protoc. 2018 Apr 18;7(4):e75.

Vasculature on the clock: Circadian rhythm and vascular dysfunction.

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Crnko S, Cour M, Van Laake LW, Lecour S. Vasculature on the clock: Circadian rhythm and vascular dysfunction. Vascul Pharmacol. 2018 May 17. pii: S1537-1891(17)30465-2.

2018, Peer Reviewed articles

Cardiovascular Benefits of Dietary Melatonin: A Myth or a Reality? 

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Jiki Z, Lecour S, Nduhirabandi F.  Cardiovascular Benefits of Dietary Melatonin: A Myth or a Reality?  Front Physiol. 2018 May 17;9:528

2018, Peer Reviewed articles

HIV treatment is associated with a twofold higher probability of raised triglycerides: pooled analyses in 21 023 individuals in sub-Saharan Africa

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K Ekoru, EH Young, DG Dillon, D Gurdasani, N Stehouwer, D Faurholt-Jepsen, NS Levitt, NJ Crowther, M Nyirenda, MA Njelekela, K Ramaiya, O Nyan, OO Adewole, K Anastos, C Compostella, JA Dave, CM Fourie, H Friis, IM Kruger, CT Longenecker, DP Maher, E Mutimura, CE Ndhlovu, G Praygod, EW Pefura Yone, M Pujades-Rodriguez, N Range, MU Sani, M Sanusi, AE Schutte, K Sliwa, PC Tien, EH Vorster, C Walsh, D Gareta, F Mashili, E Sobngwi, C Adebamowo, A Kamali, J Seeley, L Smeeth, D Pillay, AA Motala, P Kaleebu, MS Sandhu. HIV treatment is associated with a twofold higher probability of raised triglycerides: pooled analyses in 21 023 individuals in sub-Saharan Africa.  Global health, epidemiology and genomics 3

2018, Peer Reviewed articles

Prevention of infective endocarditis associated with dental interventions.

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David Jankelow, Blanche Cupido, Liesl Zühlke, Karen Sliwa, Mpiko Ntsekhe, Pravin Manga, Anton Doubell, John Lawrenson, Mohammed Rafique Essop.  Prevention of infective endocarditis associated with dental interventions.  South African Dental Journal 73 (2), 94-97

2018, Peer Reviewed articles

Influence of socioeconomic factors on pregnancy outcome in women with structural heart disease

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Iris M van Hagen, Sara Baart, Rebekah Fong Soe Khioe, Karen Sliwa-Hahnle, Nasser Taha, Malgorzata Lelonek, Luigi Tavazzi, Aldo Pietro Maggioni, Mark R Johnson, Nikolaos Maniadakis, Richard Fordham, Roger Hall, Jolien W Roos-Hesselink.  Influence of socioeconomic factors on pregnancy outcome in women with structural heart disease.  Heart. 104(9) 745-752

2018, Peer Reviewed articles

Long‐term prognosis, subsequent pregnancy, contraception and overall management of peripartum cardiomyopathy: practical guidance paper from the Heart Failure Association of the European Society of Cardiology Study Group on Peripartum Cardiomyopathy.

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Karen Sliwa, Mark C Petrie, Denise Hilfiker‐Kleiner, Alexandre Mebazaa, Alice Jackson, Mark R Johnson, Peter van der Meer, Amam Mbakwem, Johann Bauersachs.  Long‐term prognosis, subsequent pregnancy, contraception and overall management of peripartum cardiomyopathy: practical guidance paper from the Heart Failure Association of the European Society of Cardiology Study Group on Peripartum Cardiomyopathy.  European Journal of Heart Failure (2018) 20,951 –962

2018, Peer Reviewed articles

Haemorrhage and other complications in pregnant women on anticoagulation for mechanical heart valves: a prospective observational cohort study

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S Kariv, F Azibani, J Baard, A Osman, P Soma-Pillay, J Anthony, K Sliwa.  Haemorrhage and other complications in pregnant women on anticoagulation for mechanical heart valves: a prospective observational cohort study.  CARDIOVASCULAR JOURNAL OF AFRICA.  DOI: 10.5830/CVJA-2018-029

2018, Peer Reviewed articles

Achieved diastolic blood pressure and pulse pressure at target systolic blood pressure (120–140 mmHg) and cardiovascular outcomes in high-risk patients: results from ONTARGET and TRANSCEND trials.

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Michael Böhm, Helmut Schumacher, Koon K Teo, Eva Lonn, Felix Mahfoud, Johannes FE Mann, Giuseppe Mancia, Josep Redon, Roland Schmieder, Michael Weber, Karen Sliwa, Bryan Williams, Salim Yusuf.  Achieved diastolic blood pressure and pulse pressure at target systolic blood pressure (120–140 mmHg) and cardiovascular outcomes in high-risk patients: results from ONTARGET and TRANSCEND trials.  European Heart Journal (2018) 0, 1–10.

2018, Peer Reviewed articles

Rationale and design of the comparison of 3 combination therapies in lowering blood pressure in black Africans (CREOLE study): 2× 3 factorial randomized single-blind multicenter trial.

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Dike B Ojji, Neil Poulter, Albertino Damasceno, Karen Sliwa, Wynand Smythe, Nicky Kramer, Motasim Badri, Veronica Francis, Akinyemi Aje, Felix Barasa, Anastase Dzudie, Erika Jones, Shehu S Kana, Pindile Mntla, Charles Mondo, Okechukwu Ogah, Elijah N Ogola, Gboyega Ogunbanjo, Ikechi Okpechi, Gabriel Shedul, Mahmoud U Sani, Grace Shedul, Bongani M Mayosi.  Rationale and design of the comparison of 3 combination therapies in lowering blood pressure in black Africans (CREOLE study): 2× 3 factorial randomized single-blind multicenter trial.  American heart journal: 202; 5-12

2018, Peer Reviewed articles

Pharmacological Intervention to Modulate HDL: What Do We Target?

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Woudberg NJ, Pedretti S, Lecour S, Schulz R, Vuilleumier N, James RW, Frias MA. Pharmacological Intervention to Modulate HDL: What Do We Target? Front Pharmacol. 2018 Jan 22;8:989

2018, Peer Reviewed articles

Sphingosine-1-phosphate (S1P) activates STAT3 to protect against de novo acute heart failure (AHF).

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Deshpande GP, Imamdin A, Lecour S, Opie LH.  Sphingosine-1-phosphate (S1P) activates STAT3 to protect against de novo acute heart failure (AHF).  Life Sci. 2018 Mar 1;196:127-132

2018, Peer reviewed articles

The SAFE pathway for cardioprotection: is this a promising target? 

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Hadebe N, Cour M, Lecour S.  Basic Res Cardiol. The SAFE pathway for cardioprotection: is this a promising target? 2018 Jan 15;113(2):9. 

2018, Peer Reviwed articles

Extracellular vesicles in diagnostics and therapy of the ischaemic heart: Position Paper from the Working Group on Cellular Biology of the Heart of the European Society of Cardiology. 

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Sluijter JPG, Davidson SM, Boulanger CM, Buzás EI, de Kleijn DPV, Engel FB, Giricz Z, Hausenloy DJ, Kishore R, Lecour S, Leor J, Madonna R, Perrino C, Prunier F, Sahoo S, Schiffelers RM, Schulz R, Van Laake LW, Ytrehus K, Ferdinandy P.  Cardiovasc Res. Extracellular vesicles in diagnostics and therapy of the ischaemic heart: Position Paper from the Working Group on Cellular Biology of the Heart of the European Society of Cardiology. 2018 Jan 1;114(1):19-34

2018, Peer Reviewed articles

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