Publications

2018

An Exercise Intervention to Unravel the Mechanisms Underlying Insulin Resistance in a Cohort of Black South African Women: Protocol for a Randomized Controlled Trial and Baseline Characteristics of Participants. 

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Goedecke JH, Mendham AE, Clamp L, Nono Nankam PA, Fortuin-de Smidt MC, Phiri L, Micklesfield LK, Keswell D, Woudberg NJ, Lecour S, Alhamud A, Kaba M, Lutomia FM, van Jaarsveld PJ, de Villiers A, Kahn SE, Chorell E, Hauksson J, Olsson T. An Exercise Intervention to Unravel the Mechanisms Underlying Insulin Resistance in a Cohort of Black South African Women: Protocol for a Randomized Controlled Trial and Baseline Characteristics of Participants. JMIR Res Protoc. 2018 Apr 18;7(4):e75.

Vasculature on the clock: Circadian rhythm and vascular dysfunction.

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Crnko S, Cour M, Van Laake LW, Lecour S. Vasculature on the clock: Circadian rhythm and vascular dysfunction. Vascul Pharmacol. 2018 May 17. pii: S1537-1891(17)30465-2.

2018, Peer Reviewed articles

Cardiovascular Benefits of Dietary Melatonin: A Myth or a Reality? 

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Jiki Z, Lecour S, Nduhirabandi F.  Cardiovascular Benefits of Dietary Melatonin: A Myth or a Reality?  Front Physiol. 2018 May 17;9:528

2018, Peer Reviewed articles

HIV treatment is associated with a twofold higher probability of raised triglycerides: pooled analyses in 21 023 individuals in sub-Saharan Africa

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K Ekoru, EH Young, DG Dillon, D Gurdasani, N Stehouwer, D Faurholt-Jepsen, NS Levitt, NJ Crowther, M Nyirenda, MA Njelekela, K Ramaiya, O Nyan, OO Adewole, K Anastos, C Compostella, JA Dave, CM Fourie, H Friis, IM Kruger, CT Longenecker, DP Maher, E Mutimura, CE Ndhlovu, G Praygod, EW Pefura Yone, M Pujades-Rodriguez, N Range, MU Sani, M Sanusi, AE Schutte, K Sliwa, PC Tien, EH Vorster, C Walsh, D Gareta, F Mashili, E Sobngwi, C Adebamowo, A Kamali, J Seeley, L Smeeth, D Pillay, AA Motala, P Kaleebu, MS Sandhu. HIV treatment is associated with a twofold higher probability of raised triglycerides: pooled analyses in 21 023 individuals in sub-Saharan Africa.  Global health, epidemiology and genomics 3

2018, Peer Reviewed articles

Prevention of infective endocarditis associated with dental interventions.

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David Jankelow, Blanche Cupido, Liesl Zühlke, Karen Sliwa, Mpiko Ntsekhe, Pravin Manga, Anton Doubell, John Lawrenson, Mohammed Rafique Essop.  Prevention of infective endocarditis associated with dental interventions.  South African Dental Journal 73 (2), 94-97

2018, Peer Reviewed articles

Influence of socioeconomic factors on pregnancy outcome in women with structural heart disease

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Iris M van Hagen, Sara Baart, Rebekah Fong Soe Khioe, Karen Sliwa-Hahnle, Nasser Taha, Malgorzata Lelonek, Luigi Tavazzi, Aldo Pietro Maggioni, Mark R Johnson, Nikolaos Maniadakis, Richard Fordham, Roger Hall, Jolien W Roos-Hesselink.  Influence of socioeconomic factors on pregnancy outcome in women with structural heart disease.  Heart. 104(9) 745-752

2018, Peer Reviewed articles

Long‐term prognosis, subsequent pregnancy, contraception and overall management of peripartum cardiomyopathy: practical guidance paper from the Heart Failure Association of the European Society of Cardiology Study Group on Peripartum Cardiomyopathy.

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Karen Sliwa, Mark C Petrie, Denise Hilfiker‐Kleiner, Alexandre Mebazaa, Alice Jackson, Mark R Johnson, Peter van der Meer, Amam Mbakwem, Johann Bauersachs.  Long‐term prognosis, subsequent pregnancy, contraception and overall management of peripartum cardiomyopathy: practical guidance paper from the Heart Failure Association of the European Society of Cardiology Study Group on Peripartum Cardiomyopathy.  European Journal of Heart Failure (2018) 20,951 –962

2018, Peer Reviewed articles

Haemorrhage and other complications in pregnant women on anticoagulation for mechanical heart valves: a prospective observational cohort study

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S Kariv, F Azibani, J Baard, A Osman, P Soma-Pillay, J Anthony, K Sliwa.  Haemorrhage and other complications in pregnant women on anticoagulation for mechanical heart valves: a prospective observational cohort study.  CARDIOVASCULAR JOURNAL OF AFRICA.  DOI: 10.5830/CVJA-2018-029

2018, Peer Reviewed articles

Achieved diastolic blood pressure and pulse pressure at target systolic blood pressure (120–140 mmHg) and cardiovascular outcomes in high-risk patients: results from ONTARGET and TRANSCEND trials.

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Michael Böhm, Helmut Schumacher, Koon K Teo, Eva Lonn, Felix Mahfoud, Johannes FE Mann, Giuseppe Mancia, Josep Redon, Roland Schmieder, Michael Weber, Karen Sliwa, Bryan Williams, Salim Yusuf.  Achieved diastolic blood pressure and pulse pressure at target systolic blood pressure (120–140 mmHg) and cardiovascular outcomes in high-risk patients: results from ONTARGET and TRANSCEND trials.  European Heart Journal (2018) 0, 1–10.

2018, Peer Reviewed articles

Rationale and design of the comparison of 3 combination therapies in lowering blood pressure in black Africans (CREOLE study): 2× 3 factorial randomized single-blind multicenter trial.

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Dike B Ojji, Neil Poulter, Albertino Damasceno, Karen Sliwa, Wynand Smythe, Nicky Kramer, Motasim Badri, Veronica Francis, Akinyemi Aje, Felix Barasa, Anastase Dzudie, Erika Jones, Shehu S Kana, Pindile Mntla, Charles Mondo, Okechukwu Ogah, Elijah N Ogola, Gboyega Ogunbanjo, Ikechi Okpechi, Gabriel Shedul, Mahmoud U Sani, Grace Shedul, Bongani M Mayosi.  Rationale and design of the comparison of 3 combination therapies in lowering blood pressure in black Africans (CREOLE study): 2× 3 factorial randomized single-blind multicenter trial.  American heart journal: 202; 5-12

2018, Peer Reviewed articles

Pharmacological Intervention to Modulate HDL: What Do We Target?

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Woudberg NJ, Pedretti S, Lecour S, Schulz R, Vuilleumier N, James RW, Frias MA. Pharmacological Intervention to Modulate HDL: What Do We Target? Front Pharmacol. 2018 Jan 22;8:989

2018, Peer Reviewed articles

Sphingosine-1-phosphate (S1P) activates STAT3 to protect against de novo acute heart failure (AHF).

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Deshpande GP, Imamdin A, Lecour S, Opie LH.  Sphingosine-1-phosphate (S1P) activates STAT3 to protect against de novo acute heart failure (AHF).  Life Sci. 2018 Mar 1;196:127-132

2018, Peer reviewed articles

The SAFE pathway for cardioprotection: is this a promising target? 

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Hadebe N, Cour M, Lecour S.  Basic Res Cardiol. The SAFE pathway for cardioprotection: is this a promising target? 2018 Jan 15;113(2):9. 

2018, Peer Reviwed articles

Extracellular vesicles in diagnostics and therapy of the ischaemic heart: Position Paper from the Working Group on Cellular Biology of the Heart of the European Society of Cardiology. 

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Sluijter JPG, Davidson SM, Boulanger CM, Buzás EI, de Kleijn DPV, Engel FB, Giricz Z, Hausenloy DJ, Kishore R, Lecour S, Leor J, Madonna R, Perrino C, Prunier F, Sahoo S, Schiffelers RM, Schulz R, Van Laake LW, Ytrehus K, Ferdinandy P.  Cardiovasc Res. Extracellular vesicles in diagnostics and therapy of the ischaemic heart: Position Paper from the Working Group on Cellular Biology of the Heart of the European Society of Cardiology. 2018 Jan 1;114(1):19-34

2018, Peer Reviewed articles

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