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Academic Staff

Sandrine LecourProf. Sandrine Lecour
 

E-mail: Sandrine.lecour@uct.ac.za

Keywords: Cardioprotection, signaling pathways, melatonin, high density lipoproteins, SAFE pathway

Sandrine Lecour PharmD, PhD, trained at the University of Burgundy, France. She is an Associate Professor at the University of Cape Town and Leader of the Cardioprotection group at the Hatter Cardiovascular Research Institute for Africa, Department of Medicine, University of Cape Town, South Africa. Her research group focuses on the delineation of novel cardioprotective signaling pathways, including high density lipoproteins and melatonin. With the recent discovery of a novel cardioprotective signaling pathway that she has termed the SAFE (Survivor Activating Factor Enhancement) pathway, she has been invited to give lectures to international meetings such as the International Society for Heart Research meeting and the American Heart Association meeting. She has published over 60 papers in peer-reviewed journals (h index = 26). She is on the Editorial Board of Basic Research in Cardiology, Journal of Molecular and Cellular Cardiology, and on the Editorial Advisory Panel of Clinical Science. A/Prof Sandrine Lecour is a Committee Member of the ESC working group on Cellular Biology of the Heart since 2011 and a Council Member of the ISHR European section since 2014. Sandrine is a Fellow of the European Society of Cardiology and she is currently a listed grade B scientist of the South African National Research Foundation. As the founder and current the President of the South African Society for Cardiovascular Research (SASCAR), she intends to promote the research and training of students in the cardiovascular field in South Africa.

Dr Bert Mohr

E-mail: bert.mohr@uct.ac.za

BVSc (Hons), MMedVet (Med), DPhil, Dipl. ECVIM (Internal Medicine)

Dr Bert Mohr joined the University of Cape Town in November 2010 as Director of the UCT Research Animal Facility and Faculty of Health Sciences’ Veterinarian. He joined the Hatter Institute as his academic home in November 2012. Bert was born and raised in the Western Cape of South Africa. He graduated in veterinary medicine (1997) and specialised in veterinary internal medicine (2002) at the University of Pretoria, gained the Diploma of the European College of Veterinary Internal Medicine as specialist physician (2001), and following a period of lecturing in the Caribbean, obtained a DPhil (PhD) at Oxford University in human genetics (2010). Bert’s research interests include the genetic regulation of cellular adaptation to hypoxia (oxygen deficiency), molecular profiling (transcriptomics), population genetics, genomic epidemiology, genome-wide association studies, multivariate statistical modelling and the refinement of animal experiments. He is passionate about translational research, sustainable capacity building and investing in the African leaders of the future. In his free time he loves spending time with his wife, daughter and dogs; walking in nature, surfing, djembe drumming and the odd game of chess.

 

Honorary Associate Professor Gad Cotter

Born in Bucharest, Romania Jan 2nd 1964. Immigrated to Israel in 1970. Received all education in Bat-Yam a southern neighborhood of Tel-Aviv, the equivalent of South Boston on Bronx in New York. Finished public middle and high school in Bat Yam Cum Laude. Undergraduate and graduate medical school in the Hebrew university, Jerusalem. Following internship in Tel Aviv served 4 years in the Israeli army as a battalion level medical support for an infantry regiment and then the chief medical officer for Nablus. Medicine and Cardiology training in a metropolitan city in Tel Aviv were interests in research was first developed. First publication in a major journal in 2nd year of internal medicine residency. First Lancet paper in the third year of residency. By the end of fellowship published in all major CV journals, affecting patients care in heart failure and atrial fibrillation.  Started site based research center in hospital striving to bring clinical research to everyday practice. Site based research established by creating a pro-bono clinic and HF program financed by the proceedings of clinical research. All employees of clinic were compensated based on base salary and up to 150% extra for successful recruitment in clinical studies. The results have been top recruitment in studies such as TIMI studies, Enable, Veritas, all Carvedilol approval studies, etc. In parallel established site initiated research program that enabled the progress of academic fellowship programs out of metropolitan hospital making it one the most lucrative cardiovascular fellowships in Israel.

Moved to the US in 2004 to become HF faculty in Duke taking a secondary research psotion in DCRI. In 2006 established Momentum Research a privately held semi academical research organization that helps develop new interventions in HF as well as promote scientific progress and world health focusing in Africa. Momentum Research is currently eliding on 11 HF programs, representing 90% of global HF research, sponsored the first major HF initiative in Africa and is supporting dozens of manuscripts leading some of the important innovations in the HF field. 

 

Associate Professor Melinda Carrington

Melinda Carrington is Associate Professor and Centre Director for Primary Care and Prevention at the newly established Mary MacKillop Institute for Health Research with the Australian Catholic University. She is an Australian National Heart Foundation Future Leader Fellow prior to being a past recipient of prestigious National Health and Medical Research Council (NHMRC) Career Development and Early Career Fellowships. She completed her PhD at The University of Melbourne in 2007 and undertook post-doctoral training at the world renowned Baker IDI Heart and Diabetes Institute where she remained as a Lab Head until 2014. She continues to hold an Honorary appointment with Baker IDI and is an International Visiting Senior Researcher at the Hatter Institute for Cardiovascular Research in Africa, University of Cape Town, and an Adjunct Senior Research Fellow at Monash University, Melbourne, Australia.

Melinda is a Health Services Researcher undertaking large-scale risk surveillance studies and studying nurse-led models of care for cardiovascular disease and diabetes, especially in disadvantaged and vulnerable populations (e.g regional communities and Indigenous groups). Her main research interest is in the primary prevention of these conditions. Her other research interests relate to the primary care management of risk factors and the development of practical electronic tools to assist health care professionals. Over the past decade, Melinda has designed, conducted and published national outcome studies in primary care (VIPER-BP, Pressure Points); multi-site, pragmatic RCTs of multidisciplinary interventions (WHICH? & WHICH? II, NIL-CHF, Young@Heart, SAFETY) and community surveillance studies (National Blood Pressure Study, Healthy Hearts).

Melinda has over 70 original research manuscripts (>50 in the past 5 years) including Lancet, JACC and BMJ publications. She has current competitive NHMRC funding of $7.4 million and has been awarded $1.4 million in direct career support in the past 8 years. Currently, she leads a $1.3 million NHMRC Project Grant to establish regional nurse-led clinics and holds other Project Grants in Aboriginal health and chronic heart failure as well as Centre of Research Excellence funding to support teams of researchers to pursue collaborative research and develop capacity in health services research. Prior competitive and collaborative funding totals >$6 million and previous other commercial/philanthropic support totals $1.5 million, including $6.3 million for the VIPER-BP clinical trial.